Fetal and maternal candidate single nucleotide polymorphism associations with cerebral palsy: a case-control study.

Abstract

Except for the prothrombin gene mutation, individual maternal and fetal SNPs in our candidate panel were not found to be associated with CP outcome.

Past reported SNP associations with CP were not confirmed, possibly reflecting type I error from small numbers and multiple testing in the original reports.

Full Text

• DOI - Pediatrics (DOI)
• HighWire Press - full-text online
• EBSCO - full-text online

Subjects

• Adolescent
• Apolipoproteins E
• Australia
• Case-Control Studies
• Cerebral Palsy
• Child
• Child, Preschool
• Cohort Studies
• DNA Mutational Analysis
• Female
• Genetic Association Studies
• Genetic Predisposition to Disease
• Haplotypes
• Heterozygote Detection
• Humans
• Infant, Newborn
• Mannose-Binding Lectin
• Phenotype
• Polymorphism, Single Nucleotide
• Pregnancy
• Prothrombin

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Authors

• Michael E O'Callaghan
• Alastair H Maclennan
• Catherine S Gibson
• Gai L McMichael
• Eric A Haan
• Jessica L Broadbent
• Paul N Goldwater
• Jodie N Painter
• Grant W Montgomery
• Gus A Dekker

Publication date

2012-02-03

Journal

Language

Eng.

Copyright

Pediatrics

Discipline of Obstetrics and Gynaecology, School of Paediatrics and Reproductive Health, The Robinson Institute, Australia. michael.ocallaghan [at] student.adelaide.edu.au

Release reference

Pediatrics. 2012 Feb;129(2):e414-23

Related books

• Books of Apolipoproteins E
• Books of Australia
• Books of Case-Control Studies
• Books of Cerebral Palsy
• Books of Cohort Studies
• Books of DNA Mutational Analysis
• Books of Genetic Association Studies
• Books of Genetic Predisposition to Disease
• Books of Haplotypes
• Books of Heterozygote Detection
• Books of Mannose-Binding Lectin
• Books of Phenotype
• Books of Polymorphism, Single Nucleotide
• Books of Pregnancy
• Books of Prothrombin