The correlation between EEG during TH and serum NSE levels supports the hypothesis that early EEG alterations reflect permanent neuronal damage. Furthermore, this study confirms that absent EEG background reactivity and presence of epileptiform transients are robust predictors of poor outcome after CA, and that survival with good neurologic recovery is possible despite serum NSE levels> 33 μg/L. This underscores the importance of multimodal assessments in this setting.
Department of Clinical Neurosciences, University Hospital and Faculty of Biologyand Medicine, Lausanne, Switzerland. andrea.rossetti [at] chuv.ch
Neurology. 2012 Mar;78(11):796-802
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