Mapping the nerve architecture of diabetic human corneas.


Abstract

This is the first study to show an entire view of the nerve architecture in human diabetic corneas.

The decreased epithelial nerve density may result from the abnormalities of stromal nerve architecture and is affected by 5 or more years of IDDM. Although compensation for some nerve regeneration takes place, the alterations in the stromal nerves can explain the poor healing and persistent epithelial defects seen in diabetic patients.


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Publication date

2012-05-03


Journal

Ophthalmology
Ophthalmology (1549-4713)

Journal topics


Language

Eng.


Copyright

Ophthalmology

Department of Ophthalmology Louisiana State University Health Sciences Center, New Orleans, LA, USA.


Release reference

Ophthalmology. 2012 May;119(5):956-64



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