MicroRNAs and cataracts: correlation among let-7 expression, age and the severity of lens opacity.

Abstract

These findings suggest that microRNAs play a role in age-related cataracts. A local let-7b microRNA increase may represent a risk factor in the formation of age-related cataracts.

Full Text

• DOI - The British journal of ophthalmology (DOI)
• Ovid Technologies, Inc. - full-text online
• Lippincott Williams & Wilkins - full-text online
• HighWire Press - full-text online
• EBSCO - full-text online

Subjects

• Adult
• Aged
• Aged, 80 and over
• Aging
• Blotting, Western
• Cataract
• Epithelial Cells
• Female
• Gene Expression Regulation
• Humans
• Lens, Crystalline
• Male
• MicroRNAs
• Middle Aged
• Phacoemulsification
• RNA, Messenger
• Real-Time Polymerase Chain Reaction
• Risk Factors

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Authors

• Chi-Hsien Peng
• Jorn-Hon Liu
• Lin-Chung Woung
• Tzu-Jung Lin
• Shih-Hwa Chiou
• Po-Chen Tseng
• Wen-Yuan Du
• Cheng-Kuo Cheng
• Chao-Chien Hu
• Ke-Hung Chien
• Shih-Jen Chen

Publication date

2012-04-17

Journal

Journal topics

• Ophthalmology

Language

Eng.

Copyright

The British journal of ophthalmology

Department of Ophthalmology, Taipei Veterans General Hospital, No.201, Sec. 2, Shih-Pai Rd., Taipei 11217, Taiwan, ROC.

Release reference

Br J Ophthalmol. 2012 May;96(5):747-51

Related books

• Books of Aging
• Books of Blotting, Western
• Books of Cataract
• Books of Epithelial Cells
• Books of Gene Expression Regulation
• Books of Lens, Crystalline
• Books of MicroRNAs
• Books of Ophthalmology
• Books of Phacoemulsification
• Books of RNA, Messenger
• Books of Real-Time Polymerase Chain Reaction
• Books of Risk Factors