Staged implantation of multiple electrodes in the internal globus pallidus in the treatment of primary generalized dystonia.

Abstract

The addition of a second pair of electrodes in the GPi in patients with PGD with suboptimal or decaying benefit following the first surgery seems to be a safe procedure and is not followed by an increase in surgery-related complications.

This staged procedure may provide further clinical improvement in patients with PGD in whom DBS effect is initially incomplete or when disease progression occurs over time.

The position of the additional electrode within the GPi is determined by the available volume within the posteroventral GPi and by the distribution of the dystonic symptoms that need to be controlled.

Full Text

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Subjects

• Adolescent
• Adult
• Child
• Deep Brain Stimulation
• Dystonic Disorders
• Electrodes, Implanted
• Female
• Follow-Up Studies
• Globus Pallidus
• Humans
• Male
• Molecular Chaperones
• Movement
• Mutation
• Neurologic Examination
• Neurosurgical Procedures
• Patient Safety
• Treatment Outcome
• Young Adult

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Authors

• Laura Cif
• Victoria Gonzalez-Martinez
• Xavier Vasques
• Astrid Corlobé
• Ana Maria Moura
• Alain Bonafé
• Philippe Coubes

Publication date

2012-05-01

Journal

Journal topics

• Neurosurgery

Language

Eng.

Copyright

Département de Neurochirurgie, Hôpital Gui de Chauliac, Centre Hospitalier Régional Universitaire Montpellier, France. a-cif [at] chu-montpellier.fr

Release reference

J Neurosurg. 2012 May;116(5):1144-52

Related books

• Books of Deep Brain Stimulation
• Books of Dystonic Disorders
• Books of Electrodes, Implanted
• Books of Follow-Up Studies
• Books of Globus Pallidus
• Books of Molecular Chaperones
• Books of Movement
• Books of Mutation
• Books of Neurologic Examination
• Books of Neurosurgery
• Books of Neurosurgical Procedures
• Books of Patient Safety
• Books of Treatment Outcome