Metabolic manifestations of polycystic ovary syndrome in nonobese adolescents: retinol-binding protein 4 and ectopic fat deposition.

Abstract

This small preliminary study of nonobese adolescent girls suggests that RBP4 may be involved in the dyslipidemia associated with PCOS and that there may be an independent relationship between RBP4 and triglycerides but not between RBP4 and insulin resistance.

Although intrahepatic lipid content was higher in PCOS, it did not correlate with RBP4, triglycerides, or insulin resistance.

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Subjects

• Adipogenesis
• Adolescent
• Age Factors
• Analysis of Variance
• Biological Markers
• Blood Glucose
• Body Mass Index
• Case-Control Studies
• Cross-Sectional Studies
• Female
• Glucose Tolerance Test
• Hormones
• Humans
• Insulin
• Insulin Resistance
• Liver
• Pilot Projects
• Polycystic Ovary Syndrome
• Retinol-Binding Proteins, Plasma
• Triglycerides
• Young Adult

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Authors

• Aviva B Sopher
• Adrienne T Gerken
• William S Blaner
• Jeremy M Root
• Donald J McMahon
• Sharon E Oberfield

Publication date

2012-04-02

Journal

Journal topics

• Fertility
• Infertility

Language

Eng.

Copyright

Fertility and sterility

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032, USA. ahs32 [at] columbia.edu

Release reference

Fertil Steril. 2012 Apr;97(4):1009-15

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