Tumor blood flow quantified by dynamic first-pass (18)F-FDG PET/CT is significantly associated with tumor angiogenesis as evaluated by immunohistochemistry in the setting of breast cancer, whereas tumor metabolism appears to be more associated with markers of proliferation. Thus, determination of tumor blood flow and metabolism with a single injection of (18)F-FDG could be an exciting alternative to more complex and less available techniques.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Department of Nuclear Medicine, Centre Georges-François Leclerc, Dijon, France. acochet [at] cgfl.fr
J Nucl Med. 2012 Apr;53(4):512-20
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