Variation of second cancer risk by family history of retinoblastoma among long-term survivors.

Abstract

Rb survivors with bilateral disease and an inherited germline mutation are at slightly higher risk of an SC compared with those with a de novo germline mutation, in particular melanoma, perhaps because of shared genetic alterations.

Full Text

• DOI - Journal of clinical oncology : official journal of the American Society of Clinical Oncology (DOI)
• HighWire Press - full-text online
• EBSCO - full-text online

Subjects

• Adolescent
• Adult
• Child
• Female
• Follow-Up Studies
• Genetic Predisposition to Disease
• Germ-Line Mutation
• Humans
• Incidence
• Infant
• Male
• Maryland
• Middle Aged
• Neoplasms, Second Primary
• Prognosis
• Retinal Neoplasms
• Retinoblastoma
• Retinoblastoma Protein
• Retrospective Studies
• Risk Factors
• Survival Rate
• Survivors
• Young Adult

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Authors

• Ruth A Kleinerman
• Chu-Ling Yu
• Mark P Little
• Yi Li
• David Abramson
• Johanna Seddon
• Margaret A Tucker

Publication date

2012-03-19

Journal

Journal topics

• Medical Oncology

Language

Eng.

Copyright

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA. Kleinerr [at] mail.nih.gov

Release reference

J Clin Oncol. 2012 Mar;30(9):950-7

Related books

• Books of Follow-Up Studies
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• Books of Prognosis
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