Rb survivors with bilateral disease and an inherited germline mutation are at slightly higher risk of an SC compared with those with a de novo germline mutation, in particular melanoma, perhaps because of shared genetic alterations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA. Kleinerr [at] mail.nih.gov
J Clin Oncol. 2012 Mar;30(9):950-7
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