Reduce striatal uptake of FDOPA uptake indicates dysfunction of the nigrostriatal pathways in manganese toxicity secondary to end-stage liver disease.
The pattern of striatal involvement with equal reduction of FDOPA uptake in the caudate compared with posterior putamen appears different from those previously reported in individuals with occupational manganese toxicity and idiopathic Parkinson disease and may be specific to manganese toxicity secondary to end-stage liver disease.
2012-03-13
Eng.
Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA. criswells [at] neuro.wustl.edu
Arch Neurol. 2012 Mar;69(3):394-7
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