Reduction of uric acid levels with allopurinol treatment improves endothelial function in patients with chronic kidney disease.

Abstract

Treatment of hyperuricemia with allopurinol improve ED in patients with CKD. However, mechanism responsible for this beneficial effect seems to be apart from antioxidant effects of allopurinol.

Full Text

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Subjects

• Adolescent
• Adult
• Albumins
• Algorithms
• Allopurinol
• Biological Markers
• Body Mass Index
• C-Reactive Protein
• Creatinine
• Endothelium, Vascular
• Female
• Humans
• Hyperuricemia
• Lipoproteins, LDL
• Male
• Middle Aged
• P-Glycoprotein
• Prospective Studies
• Reactive Oxygen Species
• Renal Insufficiency, Chronic
• Treatment Outcome
• Tyrosine
• Uricosuric Agents

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Authors

• Berna Yelken
• Yasar Caliskan
• Numan Gorgulu
• Ibrahim Altun
• Akar Yilmaz
• Halil Yazici
• Huseyin Oflaz
• Alaattin Yildiz

Publication date

2012-03-26

Journal

Journal topics

• Kidney Diseases

Language

Eng.

Copyright

Clinical nephrology

Department of Internal Medicine, Istanbul University, Istanbul, Turkey.

Release reference

Clin Nephrol. 2012 Apr;77(4):275-82

Related books

• Books of Albumins
• Books of Algorithms
• Books of Allopurinol
• Books of Biological Markers
• Books of Body Mass Index
• Books of C-Reactive Protein
• Books of Creatinine
• Books of Endothelium, Vascular
• Books of Hyperuricemia
• Books of Kidney Diseases
• Books of Lipoproteins, LDL
• Books of P-Glycoprotein
• Books of Prospective Studies
• Books of Reactive Oxygen Species
• Books of Renal Insufficiency, Chronic
• Books of Treatment Outcome
• Books of Tyrosine
• Books of Uricosuric Agents