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Excessive antibiotic use in men with prostatitis.| Authors: | Brent C Taylor, Siamak Noorbaloochi, Mary McNaughton-Collins, Christopher S Saigal, Min-Woong Sohn, Michel A Pontari, Mark S Litwin, Timothy J Wilt, | | Language: | Eng. | | Date: | 05-05-2008 | | Journal: | The American journal of medicine
(1555-7162)
| | Release: | Am J Med. 2008 May;121(5):444-9 | |
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Abstract:
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BACKGROUND:
Prostatitis accounts for 2 million outpatient visits annually. The majority of prostatitis cases fit the definition of chronic pelvic pain syndrome, for which routine antibiotic use is not indicated.
METHODS:
Inpatient, outpatient, and pharmacy datasets from the Veterans Health Administration were used to quantify the magnitude of antibiotic use attributable to chronic pelvic pain syndrome. Specifically, men with a diagnosis of infectious/acute prostatitis or a urinary tract infection were excluded, and the remaining men with a diagnosis of prostatitis were defined as having chronic pelvic pain syndrome.
RESULTS:
The annual prevalence of chronic pelvic pain syndrome was 0.5%. Prescriptions for fluoroquinolone antibiotics were filled in 49% of men with a diagnosis of chronic pelvic pain syndrome compared with 5% in men without chronic pelvic pain syndrome. Men with chronic pelvic pain syndrome were more than 7 times more likely to receive a fluoroquinolone prescription independently of age, race/ethnicity, and comorbid conditions. Increased use of other antibiotics also was observed. High use was similar in men with either infectious/acute prostatitis or chronic pelvic pain syndrome.
CONCLUSION:
Despite evidence that antibiotics are not effective in the majority of men with chronic pelvic pain syndrome, they were prescribed in 69% of men with this diagnosis. Some increased use is probably due to uncontrolled confounding by comorbid conditions or inaccurate diagnostic coding. However, a 7-fold higher rate of fluoroquinolone usage suggests that strategies to reduce unnecessary antibiotic use in men with prostatitis are warranted.
| | Copyright: | The American journal of medicine
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA. | | Full text: |  EBSCO - HTML (needs subscription) | | Terms: | Age Distribution, Aged, Aged, 80 and over, Anti-Bacterial Agents, Drug Utilization, Humans, Male, Middle Aged, Prostatitis, Urinary Tract Infections | | |
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