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Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia.| Authors: | Arthur A M Wilde, Zahurul A Bhuiyan, Lia Crotti, Mario Facchini, Gaetano M De Ferrari, Thomas Paul, Chiara Ferrandi, Dave R Koolbergen, Attilio Odero, Peter J Schwartz | | Language: | Eng. | | Date: | 08-05-2008 | | Journal: | The New England journal of medicine
(1533-4406)
| | Release: | N Engl J Med. 2008 May;358(19):2024-9 | |
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Abstract:
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Catecholaminergic polymorphic ventricular tachycardia is a potentially lethal disease characterized by adrenergically mediated ventricular arrhythmias manifested especially in children and teenagers. Beta-blockers are the cornerstone of therapy, but some patients do not have a complete response to this therapy and receive an implantable cardioverter-defibrillator (ICD). Given the nature of catecholaminergic polymorphic ventricular tachycardia, ICD shocks may trigger new arrhythmias, leading to the administration of multiple shocks. We describe the long-term efficacy of surgical left cardiac sympathetic denervation in three young adults with catecholaminergic polymorphic ventricular tachycardia, all of whom had symptoms before the procedure and were symptom-free afterward.
| | Copyright: | The New England journal of medicine
University of Amsterdam, Amsterdam. a.a.wilde@amc.uva.nl | | Full text: |  EBSCO - HTML (needs subscription) | | Terms: | Adolescent, Catecholamines, Defibrillators, Implantable, Electrocardiography, Female, Follow-Up Studies, Heart, Humans, Male, Sympathectomy, Tachycardia, Ventricular | | |
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