Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracil.

Abstract

K(trans) measured by DCE-MRI correlated well with tumor response and survival in HCC patients who received sorafenib plus metronomic tegafur/uracil therapy.

Full Text

• DOI - Journal of Hepatology (DOI)
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Temas

• Adulto
• Anciano
• Ancianos De 80 AÑos Y Mas
• Antimetabolitos Antineoplasicos
• Agentes Antineoplasicos
• Protocolos De Quimioterapia Combinada Antineoplasica
• Bencenosulfonatos
• Marcadores Biologicos
• Carcinoma Hepatocelular
• Medios De Contraste
• Estudios De Factibilidad
• Hembra
• Humanos
• Neoplasmas Hepaticos
• Imagen Por Resonancia Magnetica
• Varón
• Middle Aged
• Neovascularizacion Patologica
• Valor Predictivo De Los Tests
• Piridinas
• Tegafur
• Uracilo
• Young Adult

Artículos similares

• Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma. (2010-06-11)
• Development of a resistance-like phenotype to sorafenib by human hepatocellular carcinoma cells is reversible and can be delayed by metronomic UFT chemotherapy. (2010-11-15)
• Impact of metronomic UFT/cyclophosphamide chemotherapy and antiangiogenic drug assessed in a new preclinical model of locally advanced orthotopic hepatocellular carcinoma. (2010-03-17)
• Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study. (2012-10-08)
• Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. (2007-08-31)
• Adjuvant therapy with protein-bound polysaccharide K and tegafur uracil in patients with stage II or III colorectal cancer: randomized, controlled trial. (2003-08-08)
• [A case of long survival with unresectable duodenal papilla cancer treated with oral chemotherapy using combination UFT and cyclophosphamide] (2008-08-14)
• A phase I study of concurrent chemoradiotherapy and cetuximab for locally advanced esophageal cancer. (2012-09-20)
• Phase II study of uracil-tegafur with leucovorin in elderly (> or = 75 years old) patients with colorectal cancer: ECOG 1299. (2007-11-30)

Autores

• Chao-Yu Hsu
• Ying-Chun Shen
• Chih-Wei Yu
• Chiun Hsu
• Fu-Chang Hu
• Chih-Hung Hsu
• Bang-Bin Chen
• Shwu-Yuan Wei
• Ann-Lii Cheng
• Tiffany Ting-Fang Shih

Fecha de publicación

2011-09-19

Revista

Temas de la revista

• Higado
• Hepatopatias

Idioma

Eng.

Copyright

Journal of Hepatology

Department of Radiology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Referencia de entrega

J Hepatol. 2011 Oct;55(4):858-65

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• Books of Agentes Antineoplasicos
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• Books of Higado
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