Emergence and dissemination of community acquired methicillin resistant Staphylococcus aureus (CA-MRSA) strains are being reported with increasing frequency in Australia and worldwide.
These strains of CA-MRSA are genetically diverse and distinct in Australia. Genotyping of CA-MRSA using eight highly-discriminatory single nucleotide polymorphisms (SNPs) is a rapid and robust method for monitoring the dissemination of these strains in the community.
In this study, a SNP genotyping method was used to investigate the molecular epidemiology of 249 community acquired non-multiresistant MRSA (nm-MRSA) isolates over a 12-month period from routine diagnostic specimens. A real-time PCR for the presence of Panton-Valentine leukocidin (PVL) was also performed on these isolates.
The CA-MRSA isolates were sourced from a large private laboratory in Brisbane, Australia that serves a wide geographic region encompassing Queensland and Northern New South Wales. This study identified 16 different STs and 98% of the CA-MRSA isolates were positive for the PVL gene.
The most common ST was ST93 with 41% of isolates testing positive for this clone.
2011-09-14
Eng.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Queensland Medical Laboratory, Brisbane, Australia.
Eur J Clin Microbiol Infect Dis. 2011 Oct;30(10):1163-7
© Galenicom 1999-2013