Serotonin 2A receptors in obsessive-compulsive disorder: a positron emission tomography study with [11C]MDL 100907.

Abstract

Adults with OCD are not characterized as a group by major changes in 5-HT(2A) availability in cortical or limbic brain regions.

Further research is warranted to examine potential differences in 5-HT(2A) availability between early- and late-onset OCD and to assess 5-HT(2A) function in relation to other neurotransmitter systems implicated in OCD.

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Temas

• Adolescente
• Adulto
• Edad De Inicio
• Hembra
• Fluorobencenos
• Humanos
• Procesamiento De Imagen Asistida Por Computador
• Marcacion Por Isotopo
• Sistema Limbico
• Imagen Por Resonancia Magnetica
• Varón
• Middle Aged
• Trastorno Obsesivo Compulsivo
• Piperidinas
• Positron-Emission Tomography
• Escalas De Valoracion Psiquiatrica
• Radiofarmacos
• Receptor, Serotonin, 5-HT2A
• Antagonistas De La Serotonina
• Young Adult

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• The influence of morphine on cerebral 5-HT2A availability in dogs: a SPECT study. (2012-10-22)
• 5-HT2A promoter polymorphism -1438G/A in children and adolescents with obsessive-compulsive disorders. (2002-12-11)
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Autores

• Helen Blair Simpson
• Mark Slifstein
• James Bender
• Xiaoyan Xu
• Elizabeth Hackett
• Michael J Maher
• Anissa Abi-Dargham

Fecha de publicación

2011-10-11

Revista

Temas de la revista

• Psiquiatria
• Psicofarmacologia
• Psicofisiologia

Idioma

Eng.

Copyright

Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA. simpson [at] nyspi.columbia.edu

Referencia de entrega

Biol Psychiatry. 2011 Nov;70(9):897-904

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