Exercise fails to improve neurocognition in depressed middle-aged and older adults.

Autori:	Benson M Hoffman, James A Blumenthal, Michael A Babyak, Patrick J Smith, Sharon D Rogers, P Murali Doraiswamy, Andrew Sherwood
Lingua:	Eng.
Data:	2008-06-26
Giornale:	Medicine and science in sports and exercise (0195-9131)
Release:	Med Sci Sports Exerc. 2008 Jul;40(7):1344-52
Abstract:	PURPOSE: Although cross-sectional studies have demonstrated an association between higher levels of aerobic fitness and improved neurocognitive function, there have been relatively few interventional studies investigating this relationship, and results have been inconsistent. We assessed the effects of aerobic exercise on neurocognitive function in a randomized controlled trial of patients with major depressive disorder (MDD). METHODS: Two-hundred and two sedentary men (n = 49) and women (n = 153), aged 40 yr and over and who met diagnostic criteria for MDD, were randomly assigned to the following: a) supervised exercise, b) home-based exercise, c) sertraline, or d) placebo pill. Before and after 4 months of treatment, participants completed measures of: Executive Function (Trail Making Test B-A difference score, Stroop Color-Word, Ruff 2
Copyright:	Medicine and science in sports and exercise Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA. Benson.Hoffman duke.edu
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