Schwannoma with monoclonal plasma cell infiltration.

Autori:	Joshua Plaut, Malcolm Galloway, Anna Childerhouse, Robert Bradford
Lingua:	Eng.
Data:	2009-09-02
Giornale:	Journal of Neurosurgery (0022-3085)
Release:	J Neurosurg. 2009 Sep;111(3):509-11
Abstract:	The authors report a very rare case of a vestibular schwannoma with an infiltrate of monoclonal plasma cells. A 45-year-old woman underwent routine excision of a presumed vestibular schwannoma. Histological analysis revealed the presence of a distinct lambda light chain restricted plasma cell population within the schwannoma. The light chain restriction and polymerase chain reaction-demonstrated monoclonality of the plasma cell population suggested the co-occurrence of a plasma cell neoplasm within a schwannoma. A search for systemic disease of plasma cell origin was unremarkable. A search of the literature suggests that this is the first report of such an occurrence.
Copyright:	Journal of Neurosurgery Department of Neurosurgery, Royal Free Hospital, London, UK. joshuaplaut googlemail.com
Full text:	DOI - Journal of Neurosurgery (DOI) Atypon - doi (ha bisogno dell'abbonamento)
Oggetto:	Female, Humans, Middle Aged, Neuroma, Acoustic, Plasma Cells