Bilateral oophorectomy and depressive symptoms 12 months after hysterectomy.

作者:	Jacqueline Rohl, Kristen Kjerulff, Patricia Langenberg, John Steege
语言:	Eng.
日期:	30-06-2008
学报:	American journal of obstetrics and gynecology (1097-6868)
发行:	Am J Obstet Gynecol. 2008 Jul;199(1):22.e1-5
摘要:	OBJECTIVE: This study was performed to examine whether bilateral oophorectomy is related to depressive symptoms. STUDY DESIGN: A secondary analysis of data collected from a cohort study of 1047 premenopausal women undergoing hysterectomy with or without concomitant oophorectomy for benign indications was performed. Data on depressive symptoms, based on the Profile of Mood States survey, were collected presurgically and 12 months postoperatively. RESULTS: The effect of bilateral oophorectomy on postoperative depressive symptoms varied, depending on the presence of baseline depressive symptoms. Bilateral oophorectomy was associated with a decrease in risk of depressive symptoms in women without baseline depressive symptoms (risk ratio [RR] 0.36 [95% confidence interval (CI), 0.17, 0.78]) and did not change significantly in those with baseline depressive symptoms (RR 1.21 [95% CI, 0.73, 2.00]). CONCLUSIONS: Bilateral oophorectomy, in comparison with unilateral or no oophorectomy, is associated with less risk of postoperative depressive symptoms in women without baseline depressive symptoms undergoing hysterectomy.
版权:	American journal of obstetrics and gynecology Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH, USA. jacqueline.rohlmd@osumc.edu
全文:	American journal of obstetrics and gynecology (DOI) Elsevier Science - HTML (需要捐款) MD Consult - HTML (需要捐款) Ovid Technologies, Inc. - HTML (需要捐款) Swets Information Services - HTML (需要捐款)